Health-Related Quality of Life and Associated Factors of Children with Transfusion-Dependent Thalassemia in Dubai, United Arab Emirates

BACKGROUND: Patients with transfusion-dependent thalassemia require lifelong blood transfusions and iron chelation therapy. Iron overload associated regular transfusion leads to a significant defect in the health-related quality of life (HRQoL) patients thalassemia. Quality has become component care, it is therefore necessary focus on HRQoL 
 OBJECTIVES: To assess children thalassemia, identify sociodemographic clinical characteristics that affect HRQoL, risk factors for poor STUDY DESIGN: A descriptive cross-sectional study was used address study’s objectives. SETTING: representative sample recruited from Dubai Thalassemia Center United Arab Emirates (UAE). PARTICIPANTS: total 68 aged 2-18 years. INTERVENTION: PedsQL 4.0 applied HRQoL. The score treated as dependent variable study. Regression analysis effect RESULTS: This included Among them, 55.9% fell into 13-18-year age group, 42.6% were male. In addition, 57.4% non-UAE nationals, 44.1% had less than 10,000 AED monthly household income. median (IQR) physical health summary 89.9 (15.6) psychosocial 90.0 (10.3). Total scores significantly higher younger children, those income, without complications. Older correlated lower total, physical, scores, whereas income scores. Controlling other variables, increasing worse CONCLUSIONS: Children their families long-term support prevention mental problems this disease.